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George Mattheolabakis Selected Research

2-(4-isobutylphenyl)propionic acid 4-(diethoxyphosphoryloxy)butyl ester

12/2014A novel ibuprofen derivative with anti-lung cancer properties: synthesis, formulation, pharmacokinetic and efficacy studies.
10/2014Pegylation improves the pharmacokinetics and bioavailability of small-molecule drugs hydrolyzable by esterases: a study of phospho-Ibuprofen.
6/2012Sterically stabilized liposomes incorporating the novel anticancer agent phospho-ibuprofen (MDC-917): preparation, characterization, and in vitro/in vivo evaluation.

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George Mattheolabakis Research Topics

Disease

23Neoplasms (Cancer)
01/2021 - 02/2009
8Lung Neoplasms (Lung Cancer)
04/2021 - 09/2013
8Pancreatic Neoplasms (Pancreatic Cancer)
01/2021 - 01/2013
3Non-Small-Cell Lung Carcinoma (Carcinoma, Non-Small Cell Lung)
01/2020 - 12/2014
2Neoplasm Metastasis (Metastasis)
01/2021 - 12/2015
2Metaplasia
10/2017 - 07/2016
2Carcinogenesis
07/2016 - 12/2014
2Adenocarcinoma
04/2016 - 02/2009
2Colonic Neoplasms (Colon Cancer)
10/2014 - 09/2013
1Intestinal Diseases (Diseases, Intestinal)
07/2021
1Gastrointestinal Diseases (Functional Gastrointestinal Disorders)
11/2019
1Inflammation (Inflammations)
11/2019
1Hodgkin Disease (Hodgkin's Disease)
01/2018
1Pancreatitis
07/2016
1Intestinal Pseudo-Obstruction (Intestinal Pseudoobstruction)
05/2016
1Glioblastoma (Glioblastoma Multiforme)
04/2016
1Autoimmune Diseases (Autoimmune Disease)
09/2015
1Experimental Arthritis
06/2013
1Osteitis
06/2013
1Arthritis (Polyarthritis)
06/2013
1Melanoma (Melanoma, Malignant)
10/2012
1Skin Neoplasms (Skin Cancer)
10/2012

Drug/Important Bio-Agent (IBA)

7Pharmaceutical PreparationsIBA
08/2019 - 06/2012
5MicroRNAs (MicroRNA)IBA
01/2021 - 12/2015
4Sulindac (Copal)FDA LinkGeneric
05/2015 - 10/2012
3Nucleic AcidsIBA
07/2021 - 07/2018
3Cisplatin (Platino)FDA LinkGeneric
01/2021 - 02/2009
32-(4-isobutylphenyl)propionic acid 4-(diethoxyphosphoryloxy)butyl esterIBA
12/2014 - 06/2012
2Epidermal Growth Factor (EGF)IBA
04/2021 - 01/2020
2RNA (Ribonucleic Acid)IBA
11/2019 - 07/2018
2Ethylene Glycol (Monoethylene Glycol)IBA
12/2018 - 10/2017
2CurcuminIBA
01/2018 - 09/2013
2Valproic Acid (Depakote)FDA LinkGeneric
10/2017 - 01/2013
2MicellesIBA
09/2016 - 09/2013
2Ibuprofen (Motrin)FDA LinkGeneric
04/2016 - 12/2014
2HydrogelsIBA
06/2013 - 10/2012
1Phosphotransferases (Kinase)IBA
01/2021
1compound 18IBA
01/2020
1LuciferasesIBA
01/2020
1PolymersIBA
08/2019
1AcidsIBA
12/2018
1Proteins (Proteins, Gene)FDA Link
01/2018
1Lipid NanoparticlesIBA
01/2018
1poly(lactic acid-ethylene glycol)IBA
10/2017
1poly(lactide) (polylactic acid)IBA
10/2017
1Platinum Compounds (Compounds, Platinum)IBA
12/2016
1SurvivinIBA
12/2016
1LipidsIBA
12/2016
1PlatinumIBA
12/2016
1Small Interfering RNA (siRNA)IBA
12/2016
1Doxorubicin (Adriamycin)FDA LinkGeneric
09/2016
1Aspirin (Acetylsalicylic Acid)FDA LinkGeneric
07/2016
1CeruletideIBA
07/2016
1GemcitabineFDA Link
04/2016
1AmidesIBA
04/2016
1SolutionsIBA
04/2016
1GelatinIBA
04/2016
1Glycerol (Glycerine)FDA LinkGeneric
04/2016
1ErbB Receptors (EGF Receptor)IBA
04/2016
1DisulfidesIBA
04/2016
1Cyclin D1IBA
04/2016
1AntagomirsIBA
01/2016
1Biomarkers (Surrogate Marker)IBA
12/2015
1RNA-Induced Silencing ComplexIBA
12/2015
1Non-Steroidal Anti-Inflammatory Agents (NSAIDs)IBA
05/2015
1Hyaluronic Acid (Hyaluronan)IBA
01/2015
1phospho-ibuprofen amideIBA
12/2014
1EsterasesIBA
10/2014
1EstersIBA
10/2014
1Carboxylic Ester HydrolasesIBA
10/2014
1Drug CombinationsIBA
09/2013
1Freund's AdjuvantIBA
06/2013
1Interleukin-6 (Interleukin 6)IBA
06/2013
1Interleukin-10 (Interleukin 10)IBA
06/2013
1Anti-Inflammatory Agents (Anti-Inflammatories)IBA
06/2013
1Poloxamer (Poloxamer 407)IBA
06/2013
1Cimetidine (Biomet)FDA LinkGeneric
01/2013
1AntigensIBA
10/2012
1Biological ProductsIBA
10/2012
1Liposomes (Liposome)IBA
06/2012
1monomethoxypolyethylene glycol (MPEG)IBA
02/2009

Therapy/Procedure

9Therapeutics
07/2021 - 10/2012
1Intralesional Injections
08/2019
1Injections
07/2016
1Cell- and Tissue-Based Therapy (Cell Therapy)
05/2016
1Immunotherapy
09/2015
1Intravenous Administration
10/2014
1Oral Administration
06/2013
1Drug Therapy (Chemotherapy)
10/2012